Does Anyone Use Brand Betapace

GENERIC Proper name: sotalol

BRAND NAME: Betapace, Betapace AF, Sorine, Sotylize

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

USES:

Sotalol is used to treat abnormal heart rhythms such as ventricular arrhythmias (for example, ventricular tachycardia) that are life threatening and atrial fibrillation. It is not used for less severe aberrant heart rhythms.
Sotalol should non exist used in patients with bronchial asthma, sinus bradycardia, second and tertiary degree AV block, unless a functioning pacemaker is present.
It likewise should non be used in people with congenital or caused long QT syndromes, cardiogenic shock, uncontrolled congestive heart failure, and people who are allergic to sotalol.

SIDE Furnishings:

Common side furnishings of sotalol include:

shortness of jiff,
dizziness,
fatigue,
palpitation,
nausea,
vomiting, and
lightheadedness.

Other side effects that may occur include:

edema (water retention),
headache,
sleep disturbances,
diarrhea,
extremity hurting,
itching,
rash,
fainting,
feet,
depression,
impotence, and
abnormal heart rhythm.

Possible serious side effects of sotalol include:

mental defoliation,
ho-hum heart charge per unit,
low claret pressure, and
chest pain

Similar other antiarrhythmic agents, sotalol tin can cause new or worsening ventricular arrhythmias (for case, ventricular tachycardia or ventricular fibrillation).

Sotalol may cause or worsen congestive centre failure, and it tin cake the symptoms of depression blood glucose in diabetics.

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PREPARATIONS: Tablets: fourscore, 120, 160, and 240 mg; oral solution: 5 mg/mL; injectable solution: 15 mg/mL

DRUG INTERACTIONS:

Combining sotalol with beta-blockers such every bit atenolol (Tenormin), propranolol (Inderal), metoprolol (Lopressor), or calcium channel blockers such as verapamil (Calan, Isoptin, Verelan, Covera-HS) or diltiazem (Cardizem, Dilacor, Tiazac), may excessively slow middle rate or cause a block in the conduction of electrical impulses through the heart. Additionally, these combinations may further reduce blood pressure, possibly leading to hypotension.
Digoxin and beta-blockers irksome conduction of impulses in the eye and decrease heart rate. Combining them tin can increase the risk of slow center rate.
Sotalol may crusade high claret glucose, and the dosage of insulin or antidiabetic drugs may crave adjustment. It also may mask symptoms of low blood glucose (hypoglycemia).
Administration of sotalol inside 2 hours of antacids containing aluminum oxide and magnesium hydroxide may reduce blood concentrations of sotalol by 26%. This reduces the effect of sotalol. This combination should be avoided or the antacid should be taken two hours afterward the sotalol.

PREGNANCY AND BREASTFEEDING SAFETY: Sotalol crosses the placenta and is found in amniotic fluid. Rubber utilize by pregnant women has not been established. Sotalol is excreted in human milk. A decision should be made whether to discontinue nursing or to discontinue the drug due to take a chance of adverse effects in the infant.

STORAGE: Shop at room temperature, xv C - 30 C (59 F - 86 F).

DOSING:

For ventricular arrhythmias and supraventricular arrhythmias the recommended dose is 80 to 160 mg orally every 12 hours or 75 to 150 mg given intravenously every 12 hours.
The recommended dose for refractory life-threatening ventricular arrhythmias is eighty to 160 mg orally every 12 hours. Doses of 160 to 640 mg/twenty-four hours given in divided doses every 8 to 12 hours may be required.
The recommended dose for atrial fibrillation or flutter is lxxx to 160 mg orally every 12 hours or 75 to 150 mg given intravenously every 12 hours.
To reduce the hazard of induced arrhythmia, patients should be observed for a minimum of iii days in a facility that tin can provide cardiac resuscitation and continuous electrocardiographic monitoring while on their maintenance dose.
The dissimilar formulations and brands of sotalol are not interchangeable.

DRUG CLASS AND Mechanism:

Sotalol is a beta-adrenergic blocking drug that is used to treat aberrant heart rhythms. Sotalol is a first generation beta blocker in a class that includes propranolol (Inderal, InnoPran), nadolol (Corgard), penbutolol sulfate (Levatol), timolol (Blocadren), and pindolol (Visken).
These drugs differ from other beta blocking drugs because they are not-selective in nature, meaning that they block both beta-1 and beta-2 receptors on nerves and, therefore, will affect not merely the centre only too the kidneys, lungs, gastrointestinal tract, liver, uterus, muscles surrounding blood vessels, and skeletal muscle.
Norepinephrine and epinephrine (adrenaline) are chemicals released inside the body that adhere to receptors on several types of cells, including fretfulness and some muscles. Attachment changes the way the cells part, either stimulating the cells or suppressing them, in part through beta receptors.
Sotalol prevents norepinephrine and epinephrine from bounden to beta receptors on nerves. By blocking the consequence of norepinephrine and epinephrine, beta blockers reduce heart rate, reduce the forcefulness of the centre's contractions, and reduce blood pressure level by relaxing the muscles surrounding the blood vessels. Sotalol also straight reduces the rate at which the centre beats past reducing the rapidity of firing of the normal generator of electrical impulses in the heart (the heart's pacemaker).
The FDA canonical sotalol in October, 1992.

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Summary

Sotalol (Betapace, Betapace AF, Sorine, Sotylize) is a drug to treat aberrant center rhythms. Sotalol reduces the firing of the hearts built-in pacemaker and it affects nerve receptors. This drug has potentially dangerous side effects and should exist prescribed with caution.

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Related Disease Weather

Atrial Fibrillation (AFib) Treatment Drugs

Atrial fibrillation (AFib) is a center rhythm disorder that causes irregular and often rapid heartbeat. The medications to treat AFib include beta-blockers, claret thinners, and heart rhythm drugs. Atrial fibrillation drugs can cause serious side effects like seizures, vision changes, shortness of breath, fainting, other aberrant center rhythms, excessive bleeding while coughing or vomiting, blood in the stool, and bleeding into the brain.
Atrial Flutter: ECG, Symptoms, and Treatments

Atrial flutter is a problem with the atria of the heart. In atrial flutter the atria of the heart speedily and repeatedly beat due to an anomaly in the electrical system of the heart. It is a type of arrhythmia and can be unsafe considering complications can develop easily. Signs and symptoms of atrial palpitate include near fainting, palpitations, mild shortness of jiff, and fatigue. While the verbal cause of atrial flutter is non clearly understood, information technology's near probable related to your health, what medical conditions yous certainly take, poor diet, lack of exercise, and drinking too much alcohol. Atrial flutter is diagnosed past physical examination, medical history, and a sawtooth ECG moving ridge pattern.

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In the U.S., i in every 4 deaths is caused past center disease. Run across Answer

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that apply of particular drug is condom, appropriate or effective for you or anyone else. A healthcare professional should be consulted earlier taking any drug, changing any diet or commencing or discontinuing any course of treatment.

References

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